Emory Biomarker Service Center
The Emory Biomarker Service Center (EBSC) supports all Woodruff Health Science Center (WHSC) investigators as well as local, national, and international invesigators in health science. The EBSC is non-profit and focuses on the application of high-throughput genetic and molecular techniques for disease research in a translational setting. This includes molecular characterization, susceptibility genetic association studies, analysis, validation, and diagnostic development in a CLIA (CLIA # 11D1086150) certified environment.
Project Application Process
Want to utilize EBSC services? The process for applying for services is simple. Please see our protocols page
Background
The Emory Biomarker Service Center (EBSC) is the synergistic integration of the former Center for Medical Genomics (CMG), Yerkes Microarray Core (YMC), and the Winship Cancer Institute Microarray Core (WCIMC) facilities into one lab with complementary capabilities, goals, and services. By integrating into one shared core and facility we have leveraged knowledge and resources to provide comprehensive services for investigators at Emory University, Emory Healthcare, and the entire health care and research communities.
Key Goals
- Place state of the art tools and technologies within reach of investigators catalyzing translational disease research through basic science
- Assist investigators in novel multi-disciplinary approaches in genomic, epi-genomic, proteomic, and pharmacogenomic fields for the efficacious and safe application of medicine through both prognostic and predictive biomarkers
Publications
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells.
Scharer CD, McCabe CD, Ali-Seyed M, Berger MF, Bulyk ML, Moreno CS.
Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II.
Feigelson HS, Teras LR, Diver WR, Tang W, Patel AV, Stevens VL, Calle EE, Thun MJ, Bouzyk M.
Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells.
Guo L, Zhong D, Lau S, Liu X, Dong XY, Sun X, Yang VW, Vertino PM, Moreno CS, Varma V, Dong JT, Zhou W.
The endothelin-1 G5665T polymorphism impacts transplant-free survival for single ventricle patients.
Kirshbom PM, Mahle WT, Joyner RW, Leong T, Wilson M, Kogon BE, Kanter KR, Bouzyk MM.
Optimization of RNA extraction from FFPE tissues for expression profiling in the DASL assay.
Abramovitz M, Ordanic-Kodani M, Wang Y, Li Z, Catzavelos C, Bouzyk M, Sledge GW Jr, Moreno CS, Leyland-Jones B.
Intercenter reliability and validity of the rhesus macaque GeneChip.
Duan F, Spindel ER, Li YH, Norgren RB Jr.
Genome-wide analysis of the homeobox C6 transcriptional network in prostate cancer.
McCabe CD, Spyropoulos DD, Martin D, Moreno CS.
Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness.
Ahmad S, Tang W, Chang Q, Qu Y, Hibshman J, Li Y, Söhl G, Willecke K, Chen P, Lin X.
A new method for identifying informative genetic markers in selectively bred rats.
Weinshenker D, Wilson MM, Williams KM, Weiss JM, Lamb NE, Twigger SN.
Posters
Molecular differences in triple negative breast cancer between race/ethnicities.
Bouzyk MM, Barwick BG, Abramovitz M, Kodani M, Oprea G, Tang W, Moreno CS, Leyland-Jones B
Development of a Prognostic Biomarker Protein Array for the Cerebrospinal Fluid (CSF) of Brain Tumor Patients.
Li Y, Khwaja F, Wagar N, Bouzyk M and Van Meir EG
MicroRNA Involvement in Breast Cancer Multidrug Resistance
Liang Z, Wu H, Xia J, Li YH, Wagar N, Zhu A, Wang S, Blevins D, Yoon Y, Reddy S, Southerland J, Scala S, Bates S, Shim H.
The Role of Sex Hormone-Binding Globulin (SHBG) in the Androgen Response of Human Prostate Cancer Cells
Li YH, Nakhla A, Hryb D, Friedman R, Xiang J, Wagar N, Rosner W, Romas N, Klatt D and Kahn S
Genome-wide Analysis of Gene Expression Profiles Induced by Norwalk Virus Capsid Protein Gene
Liu P, Li YH, Hsiao H, Wagar N, Moe CL
Microarray Analysis of Apoptosis-associated Pathways in Connexin30-deficient Cochlea
Tang W, Li YH, Qu Y, Wagar N, and Lin X
The Center for Medical Genomics Overview
Wilson M
The Winship Cancer Institute Microarray Core Facility
Kodani M
Yerkes Microarray Core
Wagar N, Li YH
Acknowledgement & Authorhship
The Core Facilities at Emory are here to support your research. In order to ensure that the appropriate recognition is attributed to the facilities, please acknowledge the facilities on all publications.