Service Center Facilities
Home
School of Medicine Service Centers
Emory Service Centers

Success Rate

Service provision and Efficiency records for Calendar year 2007:

Transgenic Production:

  1. Initiated 21 independent projects for 13 Emory Investigators
  2. Achieved 100% success rate (minimum of 2 founder lines for all 21 projects)
  3. Generated 51 independent founder lines utilizing standard plasmid constructs in either C57BL/6 or FVB/N background.
  4. Produced 15 founder lines from BAC constructs in FVB/N representing 6 independent projects
  5. Total transgenic founder rate of 10% (Range from 2% to 36%)

ff

Gene Targeting:

  1. Initiated 13 gene targeting projects for 11 Emory investigators, and one external investigator.
  2. Completed Projects (five):
    1. 100% success rate for germline transmission.
    2. Average number of correctly targeted clones: 15
    3. Average targeting efficiency: 8%
    4. Average number of chimeric males >90% from Blast injection: 11

imagebar