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Selected publications in this area:

1. Madsen MT, Anderson JA, Halama JR, Kleck J, Simpkin DJ, Votaw JR, Wendt RE 3rd, Williams LE, Yester MV. AAPM Task Group 108: PET and PET/CT shielding requirements. Med Phys. 2006 Jan;33(1):4-15. Erratum in: Med Phys. 2006 Sep;33(9):3579. PubMed PMID: 16485403.

2. Zeng F, Southerland JA, Voll RJ, Votaw JR, Williams L, Ciliax BJ, Levey AI, Goodman MM. Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease. Bioorg Med Chem Lett. 2006 Jun 1;16(11):3015-8. Epub 2006 Mar 29. PubMed PMID: 16574411.

3. Howell LL, Carroll FI, Votaw JR, Goodman MM, Kimmel HL. Effects of combined dopamine and serotonin transporter inhibitors on cocaine self-administration in rhesus monkeys. J Pharmacol Exp Ther. 2007 Feb;320(2):757-65. Epub 2006 Nov 14. PubMed PMID: 17105829.

4. Stehouwer JS, Jarkas N, Zeng F, Voll RJ, Williams L, Owens MJ, Votaw JR, Goodman MM. Synthesis, radiosynthesis, and biological evaluation of carbon-11 labeled 2beta-carbomethoxy-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography. J Med Chem. 2006 Nov 16;49(23):6760-7. PubMed PMID: 17154506.

5. Oka S, Hattori R, Kurosaki F, Toyama M, Williams LA, Yu W, Votaw JR, Yoshida Y, Goodman MM, Ito O. A preliminary study of anti-1-amino-3-18F-fluorocyclobutyl-1-carboxylic acid for the detection of prostate cancer. J Nucl Med. 2007 Jan;48(1):46-55. PubMed PMID: 17204698.

6. Schuster DM, Votaw JR, Nieh PT, Yu W, Nye JA, Master V, Bowman FD, Issa MM, Goodman MM. Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma. J Nucl Med. 2007 Jan;48(1):56-63. PubMed PMID: 17204699.

7. Zeng F, Stehouwer JS, Jarkas N, Voll RJ, Williams L, Camp VM, Votaw JR, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of 2beta,3alpha-(substituted phenyl)nortropanes as potential norepinephrine transporter imaging agents. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3044-7. Epub 2007 Mar 23. PubMed PMID: 17446069.

8. Nye JA, Schuster DM, Yu W, Camp VM, Goodman MM, Votaw JR. Biodistribution and radiation dosimetry of the synthetic nonmetabolized amino acid analogue anti-18F-FACBC in humans. J Nucl Med. 2007 Jun;48(6):1017-20. Epub 2007 May 15. PubMed PMID: 17504867.

9. Innis RB, Cunningham VJ, Delforge J, Fujita M, Gjedde A, Gunn RN, Holden J, Houle S, Huang SC, Ichise M, Iida H, Ito H, Kimura Y, Koeppe RA, Knudsen GM, Knuuti J, Lammertsma AA, Laruelle M, Logan J, Maguire RP, Mintun MA, Morris ED, Parsey R, Price JC, Slifstein M, Sossi V, Suhara T, Votaw JR, Wong DF, Carson RE. Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J
Cereb Blood Flow Metab. 2007 Sep;27(9):1533-9. Epub 2007 May 9. Review. PubMed PMID: 17519979.

10. Nye JA, Esteves F, Votaw JR. Minimizing artifacts resulting from respiratory and cardiac motion by optimization of the transmission scan in cardiac PET/CT. Med Phys. 2007 Jun;34(6):1901-6. PubMed PMID: 17654891.

11. Plisson C, Stehouwer JS, Voll RJ, Howell L, Votaw JR, Owens MJ, Goodman MM. Synthesis and in vivo evaluation of fluorine-18 and iodine-123 labeled 2beta-carbo(2-fluoroethoxy)-3beta-(4'-((Z)-2- iodoethenyl)phenyl)nortropane as a candidate serotonin transporter imaging agent. J Med Chem. 2007 Sep 20;50(19):4553-60. Epub 2007 Aug 17. PubMed PMID: 17705359.

12. Rilling JK, Barks SK, Parr LA, Preuss TM, Faber TL, Pagnoni G, Bremner JD, Votaw JR. A comparison of resting-state brain activity in humans and chimpanzees. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17146-51. Epub 2007 Oct 16. PubMed PMID: 17940032; PubMed Central PMCID: PMC2040430.

13. Votaw JR, Martin D. Modeling systemic and renal gadolinium chelate transport with MRI. Pediatr Radiol. 2008 Jan;38 Suppl 1:S28-34. Epub 2007 Dec 11. PubMed PMID: 18074127.

14. Jarkas N, Voll RJ, Williams L, Votaw JR, Owens M, Goodman MM. Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as
PET serotonin transporter ligand
s. J Med Chem. 2008 Jan 24;51(2):271-81. Epub 2007 Dec 18. PubMed PMID: 18085744.

15. Martin DR, Sharma P, Salman K, Jones RA, Grattan-Smith JD, Mao H, Lauenstein TC, Burrow BK, Tudorascu DL, Votaw JR. Individual kidney blood flow measured with contrast-enhanced first-pass perfusion MR imaging. Radiology. 2008 Jan;246(1):241-8. PubMed PMID: 18096538.

16. Kalb B, Votaw JR, Salman K, Sharma P, Martin DR. Magnetic resonance nephrourography: current and developing techniques. Radiol Clin North Am. 2008 Jan;46(1):11-24, v. Review. PubMed PMID: 18328877.

17. Rilling JK, Lacreuse A, Barks SK, Elfenbein HA, Pagnoni G, Votaw JR, Herndon JG. Effect of menstrual cycle on resting brain metabolism in female rhesus monkeys. Neuroreport. 2008 Mar 26;19(5):537-41. PubMed PMID: 18388734.

18. Schuster DM, Halkar RK, Esteves FP, Garcia EV, Cooke CD, Syed MA, Bowman FD, Votaw JR. Investigation of emission-transmission misalignment artifacts on rubidium-82 cardiac PET with adenosine pharmacologic stress. Mol Imaging Biol. 2008 Jul-Aug;10(4):201-8. Epub 2008 May 3. PubMed PMID: 18454300.

19. Kimmel HL, Negus SS, Wilcox KM, Ewing SB, Stehouwer J, Goodman MM, Votaw JR, Mello NK, Carroll FI, Howell LL. Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys. Pharmacol Biochem Behav. 2008 Sep;90(3):453-62. Epub 2008 Apr 4. PubMed PMID: 18468667; PubMed Central PMCID: PMC2453312.

20. Nye JA, Votaw JR, Jarkas N, Purselle D, Camp V, Bremner JD, Kilts CD, Nemeroff CB, Goodman MM. Compartmental modeling of 11C-HOMADAM binding to the serotonin transporter in the healthy human brain. J Nucl Med. 2008 Dec;49(12):2018-25. PubMed PMID: 19038997.

21. Stehouwer JS, Jarkas N, Zeng F, Voll RJ, Williams L, Camp VM, Malveaux EJ, Votaw JR, Howell L, Owens MJ, Goodman MM. Synthesis, radiosynthesis, and biological evaluation of fluorine-18-labeled
2beta-carbo(fluoroalkoxy)-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography
. J Med Chem. 2008 Dec 25;51(24):7788-99. PubMed PMID: 19053782; PubMed Central PMCID: PMC2668213.

22. Zeng F, Mun J, Jarkas N, Stehouwer JS, Voll RJ, Tamagnan GD, Howell L, Votaw JR, Kilts CD, Nemeroff CB, Goodman MM. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter. J Med Chem. 2009 Jan 8;52(1):62-73. PubMed PMID: 19067522; PubMed Central PMCID: PMC2746395.

23. Parr LA, Hecht E, Barks SK, Preuss TM, Votaw JR. Face processing in the chimpanzee brain. Curr Biol. 2009 Jan 13;19(1):50-3. Epub 2008 Dec 18. PubMed PMID: 19097899; PubMed Central PMCID: PMC2651677.

24. Raghunath N, Faber TL, Suryanarayanan S, Votaw JR. Motion correction of PET brain images through deconvolution: II. Practical implementation and algorithm optimization. Phys Med Biol. 2009 Feb 7;54(3):813-29. Epub 2009 Jan 9. PubMed PMID: 19131667.

25. Faber TL, Raghunath N, Tudorascu D, Votaw JR. Motion correction of PET brain images through deconvolution: I. Theoretical development and analysis in software simulations. Phys Med Biol. 2009 Feb 7;54(3):797-811. Epub 2009 Jan 9. PubMed PMID: 19131672.

26. Fantegrossi WE, Bauzo RM, Manvich DM, Morales JC, Votaw JR, Goodman MM, Howell LL. Role of dopamine transporters in the behavioral effects of 3,4-methylenedioxymethamphetamine (MDMA) in nonhuman primates. Psychopharmacology (Berl). 2009 Aug;205(2):337-47. Epub 2009 May 7. PubMed PMID: 19421742.

27. Schuster DM, Nye JA, Nieh PT, Votaw JR, Halkar RK, Issa MM, Yu W, Sepulveda J, Zeng W, Young A, Goodman MM. Initial experience with the radiotracer anti-1-amino-3-[18F]Fluorocyclobutane-1-carboxylic acid (anti-[ 18F]FACBC) with PET in renal carcinoma. Mol Imaging Biol. 2009 Nov-Dec;11(6):434-8. Epub 2009 May 16. PubMed PMID: 19449079.

28. Nye JA, Hamill J, Tudorascu D, Carew J, Esteves F, Votaw JR. Comparison of low-pitch and respiratory-averaged CT protocols for attenuation correction of cardiac PET studies. Med Phys. 2009 May;36(5):1618-23. PubMed PMID: 19544778.

29. Howell LL, Votaw JR, Goodman MM, Lindsey KP. Cortical activation during cocaine use and extinction in rhesus monkeys. Psychopharmacology (Berl). 2010 Feb;208(2):191-9. Epub 2009 Nov 19. PubMed PMID: 19924404; PubMed Central PMCID: PMC2819208.

30. Esteves FP, Nye JA, Khan A, Folks RD, Halkar RK, Garcia EV, Schuster DM, Lerakis S, Raggi P, Votaw JR. Prompt-gamma compensation in Rb-82 myocardial perfusion 3D PET/CT. J Nucl Cardiol. 2010 Apr;17(2):247-53. Epub 2009 Nov 24. PubMed PMID: 19937169.

31. Kalb B, Votaw JR, Salman K, Sharma P, Martin DR. Magnetic resonance nephrourography: current and developing techniques. Magn Reson Imaging Clin N Am. 2010 Feb;18(1):29-42. PubMed PMID: 19962091.

32. Nye JA, Dubose M, Votaw JR. A comparison of AAPM TG-108 PET/CT shielding recommendations to measurements in an oncology center. Med Phys. 2009 Nov;36(11):5017-21. PubMed PMID: 19994511.

33. Kalb B, Votaw JR, Sharma P, Salman K, Ghafourian P, Martin DR. Magnetic resonance nephrourographic techniques and applications: how we do it. Top Magn Reson Imaging. 2009 Apr;20(2):59-69. Review. PubMed PMID: 20010060.

34. Stehouwer JS, Daniel LM, Chen P, Voll RJ, Williams L, Plott SJ, Votaw JR, Owens MJ, Howell L, Goodman MM. Synthesis, fluorine-18 radiolabeling, and biological evaluation of N-((E)-4-fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-halophenyl)nortropanes : candidate radioligands for in vivo imaging of the brain dopamine transporter with positron emission tomography. J Med Chem. 2010 Aug 12;53(15):5549-57. PubMed PMID: 20597489.

35. Henry PK, Murnane KS, Votaw JR, Howell LL. Acute brain metabolic effects of cocaine in rhesus monkeys with a history of cocaine use. Brain Imaging Behav. 2010 Dec;4(3-4):212-9. PubMed PMID: 20680706.

36. Zeng W, Sepulveda JN, Nye J, Votaw JR, Nieh PT, Carew J, Schuster DM. Posterior bladder layering of excreted 18F-FDG on PET/CT. Nucl Med Commun. 2010 Oct;31(10):859-63. PubMed PMID: 20700066.

37. Jones RA, Votaw JR, Salman K, Sharma P, Lurie C, Kalb B, Martin DR. Magnetic resonance imaging evaluation of renal structure and function related to disease: technical review of image acquisition, postprocessing, and mathematical modeling steps. J Magn Reson Imaging. 2011 Jun;33(6):1270-83. doi: 10.1002/jmri.22335.PubMed PMID: 21590995.

38. Masilamoni GJ, Bogenpohl JW, Alagille D, Delevich K, Tamagnan G, Votaw JR, Wichmann T, Smith Y. Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys. Brain. 2011 Jul;134(Pt 7):2057-73. PubMed PMID: 21705423; PubMed Central PMCID: PMC3122374.

39. Nye JA, Avila-Rodriguez MA, Nickles RJ. A grid-mounted niobium body target for the production of reactive [18F]fluoride. Appl Radiat Isot. 2006 May;64(5):536-9. Epub 2005 Dec 20. PubMed PMID: 16368243.

40. Nye JA, Avila-Rodriguez MA, Nickles RJ. A new binary compound for the production of 124I via the 124Te(p,n)124I reaction. Appl Radiat Isot. 2007 Apr;65(4):407-12. Epub 2006 Dec 14. PubMed PMID: 17174098.

41. Avila-Rodriguez MA, Nye JA, Nickles RJ. Simultaneous production of high specific activity 64Cu and 61Co with 11.4 MeV protons on enriched 64Ni nuclei. Appl Radiat Isot. 2007 Oct;65(10):1115-20. Epub 2007 Jul 3. PubMed PMID: 17669663.

42. Avila-Rodriguez MA, Nye JA, Nickles RJ. Production and separation of non-carrier-added 86Y from enriched 86Sr targets. Appl Radiat Isot. 2008 Jan;66(1):9-13. Epub 2007 Aug 9. PubMed PMID: 17869530.

43. Esteves FP, Sanyal R, Nye JA, Santana CA, Verdes L, Raggi P. Adenosine stress rubidium-82 PET/computed tomography in patients with known and suspected coronary artery disease. Nucl Med Commun. 2008 Aug;29(8):674-8. PubMed PMID: 18753818.

44. Esteves FP, Khan A, Correia LC, Nye JA, Halkar RK, Schuster DM, Stillman A, Raggi P. Absent coronary artery calcium excludes inducible myocardial ischemia on computed tomography/positron emission tomography. Int J Cardiol. 2011 Mar 17;147(3):424-7. Epub 2009 Nov 4. PubMed PMID: 19892417.

45. Schreibmann E, Nye JA, Schuster DM, Martin DR, Votaw J, Fox T. MR-based attenuation correction for hybrid PET-MR brain imaging systems using deformable image registration. Med Phys. 2010 May;37(5):2101-9. PubMed PMID: 20527543.

46. Savir-Baruch B, Schuster DM, Jarkas N, Master VA, Nieh PT, Halkar RK, Nye JA, Lewis MM, Crowe RJ, Voll RJ, Camp VM, Bellamy LM, Roberts DL, Goodman MM. Pilot Evaluation of Anti-1-amino-2-[(18)F] fluorocyclopentane-1-carboxylic acid (anti-2-[(18)F] FACPC) PET-CT in Recurrent Prostate Carcinoma. Mol Imaging Biol. 2010 Oct 26. [Epub ahead of print] PubMed PMID: 20976627; PubMed Central PMCID:

47. Schuster DM, Savir-Baruch B, Nieh PT, Master VA, Halkar RK, Rossi PJ, Lewis MM, Nye JA, Yu W, Bowman FD, Goodman MM. Detection of recurrent prostate carcinoma with anti-1-amino-3-18F- fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT. Radiology. 2011 Jun;259(3):852-61. Epub 2011 Apr 14. PubMed PMID: 21493787; PubMed Central PMCID: PMC3099047.

48. Nye JA, Faber TL. Current state of hybrid imaging: attenuation correction and fusion. J Nucl Cardiol. 2011 Aug;18(4):729-40. Epub 2011 May 7. PubMed PMID:21553160.